FRESH INSIGHTS INTO THE PYRIMIDINE METABOLISM IN THE TRYPANOSOMATIDS


A computational framework for testing hypotheses of the minimal mechanical requirements for cell aggregation using early annual killifish embryogenesis as a model

Introduction: Deciphering the biological and physical requirements for the outset of multicellularity is limited to few experimental models.The early embryonic development of annual killifish represents an almost unique opportunity to investigate de novo cellular aggregation in a vertebrate model.As an adaptation to seasonal drought, annual killifi

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Human ATP-binding cassette (ABC) transporter family

Abstract There exist four fundamentally different classes of membrane-bound transport proteins: ion channels; transporters; aquaporins; and ATP-powered pumps.ATP-binding cassette (ABC) transporters are an example Door Seal End of ATP-dependent pumps.ABC transporters are ubiquitous membrane-bound proteins, present in all prokaryotes, as well as plan

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